Param-Medic: A Tool for Improving MS/MS Database Search Yield by Optimizing Parameter Settings
نویسندگان
چکیده
منابع مشابه
Param-Medic: A Tool for Improving MS/MS Database Search Yield by Optimizing Parameter Settings.
In shotgun proteomics analysis, user-specified parameters are critical to database search performance and therefore to the yield of confident peptide-spectrum matches (PSMs). Two of the most important parameters are related to the accuracy of the mass spectrometer. Precursor mass tolerance defines the peptide candidates considered for each spectrum. Fragment mass tolerance or bin size determine...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2017
ISSN: 1535-3893,1535-3907
DOI: 10.1021/acs.jproteome.7b00028